The first episode of the podcast was released on 19th February 2024, where Samantha along with her friend Alkesh educates the viewers on what autoimmunity is and why autoimmune cases are increasing surprisingly. An autoimmune condition is when our immune system can’t differentiate normal cells from foreign cells and mistakenly attacks normal cells causing problems. Samantha is surprised by the number of autoimmune cases that has been surprisingly increasing to which Alkesh explains the reason behind it, Stress, Bad Eating Habits, and Overemphasis on Work or Career could be the major reasons for the rise in autoimmune conditions. Furthermore, Samantha and Alkesh discuss the toxic input and detox output, how can one prevent too much toxic input, and how proper sleep helps in body detox. Apart from this, Samantha shares the hurdles she faced trying to fight through this condition. Alkesh then gives the viewers 3 takeaways to prevent Autoimmunity, which include, Eating a Clean Diet, that is, minimally processed food, drinking filtered water (add a pinch of Himalayan pink salt on your drinking water), Use Clean Personal Care Products, one’s deodorants, makeup production which contains clean ingredients, de-stress yourself now and then, and move more frequently, don’t be stagnant. 

She was last seen in the movie Kushi (2023), where she played a pivotal role alongside famous actor Vijay Devarakonda. The film narrates an interesting tale of a young man who grows up in an atheist household and falls in love with the daughter of his father’s arch-rival, a devout Hindu leader. Samantha then went on to finish her parts in the highly anticipated TV series, Citadel, where she played the role of Nadia Sinh’s (Priyanka Chopra) mother and decided to take a break from the film industry, Samantha is now back in the industry and hosts a health podcast named Take20.